Sex and the Single Splice

تأثیر آدنوزین ´5تری فسفات در القای آپوپتوز و مهار بیان ژن Survivin و واریانت پیرایشی ضد آپوپتوزی SUR-3B آن در سلول های K562

Introduction: Leukemia is a heterogeneous malignant disease in which progression at the level of CD34+ cells has a major impact in drug resistance and relapse. The multi-drug resistance gene product, P-glycoprotein is an inhibitor of apoptosis proteins (IAPs), such as Survivin that are expressed simultaneously with several putative drug resistance parameters in CD34+ leukemia cells. In fact, IA...

Splice Graphs and their Vertex-Degree-Based Invariants

Let G_1 and G_2 be simple connected graphs with disjoint vertex sets V(G_1) and V(G_2), respectively. For given vertices a_1in V(G_1) and a_2in V(G_2), a splice of G_1 and G_2 by vertices a_1 and a_2 is defined by identifying the vertices a_1 and a_2 in the union of G_1 and G_2. In this paper, we present exact formulas for computing some vertex-degree-based graph invariants of splice of graphs.

Assessment of genetic diversity among and within Iranian chamomile populations using semi random intron-exon splice junction (ISJ) markers

Chamomile (Matricaria chamomilla), an important medicinal plant belonging to the Asteraceae family, has a wide distribution in Iran and other parts of the world. The medicinal and pharmacological effects of chamomile are mainly associated with its essential oil content and it is widely used in food, cosmetics and pharmaceutical industries. Despite its wide geographical distribution in Iran, lit...

Fragility Curves for Reinforced Concrete Frames with Lap-Spliced Columns

Placing column lap-splice in the locations of possible nonlinear deformation may adversely affect the structures response to strong ground motions. Localization of damage in splice zone may change the structural response and prevent the load redistribution and development of a uniform pattern of nonlinear excursions among the various members. Validated by existing laboratory experiments, this s...

Regulation of sex-specific selection of fruitless 5' splice sites by transformer and transformer-2.

In Drosophila melanogaster, the fruitless (fru) gene controls essentially all aspects of male courtship behavior. It does this through sex-specific alternative splicing of the fru pre-mRNA, leading to the production of male-specific fru mRNAs capable of expressing male-specific fru proteins. Sex-specific fru splicing involves the choice between alternative 5' splice sites, one used exclusively ...

Comparison of Expression of Growth Hormone-Releasing Hormone and Its Receptor Splice Variant 1 in Different Stages of Endometriosis